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BAIAP2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00010458-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BAIAP2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 60.83
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BAIAP2 antibody (H00010458-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00010458-T01
    BAIAP2 transfected lysate.
    Western Blot
    QC Testing of H00010458-T01
    Lane 1: BAIAP2 transfected lysate ( 60.83 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • BAIAP2
  • Gene Alias:
  • BAP2,IRSP53
  • Gene Description:
  • BAI1-associated protein 2
  • Gene Summary:
  • The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
  • Other Designations:
  • insulin receptor substrate p53
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