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BAIAP2 (Human) IP-WB Antibody Pair

  • Catalog # : H00010458-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00010458-PW1
    Immunoprecipitation of BAIAP2 transfected lysate using mouse monoclonal anti-BAIAP2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-BAIAP2.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-BAIAP2 (300 ug)
    2. Antibody pair for WB: rabbit polyclonal anti-BAIAP2 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Gene Name:
  • BAIAP2
  • Gene Alias:
  • BAP2,IRSP53
  • Gene Description:
  • BAI1-associated protein 2
  • Gene Summary:
  • The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
  • Other Designations:
  • insulin receptor substrate p53
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