LRRN5 monoclonal antibody (M01), clone 6A9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LRRN5.
Immunogen
LRRN5 (NP_006329, 532 a.a. ~ 630 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of LRRN2 expression in transfected 293T cell line by LRRN5 monoclonal antibody (M01), clone 6A9.
Lane 1: LRRN2 transfected lysate (Predicted MW: 78.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged LRRN2 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — LRRN2
Entrez GeneID
10446GeneBank Accession#
NM_006338Protein Accession#
NP_006329Gene Name
LRRN2
Gene Alias
FIGLER7, GAC1, LRANK1, LRRN5
Gene Description
leucine rich repeat neuronal 2
Omim ID
605492Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034222|OTTHUMP00000035083|OTTHUMP00000035084|fibronectin type III, immunoglobulin and leucine rich repeat domain 7|glioma amplified on chromosome 1|leucine rich and ankyrin repeats 1|leucine rich repeat neuronal 5
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Interactome
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Disease
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