LRRN2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LRRN2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LRRN2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LRRN2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LRRN2
Entrez GeneID
10446GeneBank Accession#
LRRN2Gene Name
LRRN2
Gene Alias
FIGLER7, GAC1, LRANK1, LRRN5
Gene Description
leucine rich repeat neuronal 2
Omim ID
605492Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034222|OTTHUMP00000035083|OTTHUMP00000035084|fibronectin type III, immunoglobulin and leucine rich repeat domain 7|glioma amplified on chromosome 1|leucine rich and ankyrin repeats 1|leucine rich repeat neuronal 5
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Interactome
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Disease
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