CD2BP2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CD2BP2 full-length ORF ( AAH00495, 1 a.a. - 341 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRERPPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGRKGPGQPSSPQRLDRLSGLADQMVARGNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
63.25
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CD2BP2
Entrez GeneID
10421GeneBank Accession#
BC000495Protein Accession#
AAH00495Gene Name
CD2BP2
Gene Alias
FWP010, LIN1, Snu40, U5-52K
Gene Description
CD2 (cytoplasmic tail) binding protein 2
Omim ID
604470Gene Ontology
HyperlinkGene Summary
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD2 antigen (cytoplasmic tail) binding protein 2|CD2 binding protein 2|CD2 cytoplasmic domain binding protein 2|U5 snRNP 52K protein
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