CD2BP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CD2BP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CD2BP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CD2BP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CD2BP2
Entrez GeneID
10421GeneBank Accession#
CD2BP2Gene Name
CD2BP2
Gene Alias
FWP010, LIN1, Snu40, U5-52K
Gene Description
CD2 (cytoplasmic tail) binding protein 2
Omim ID
604470Gene Ontology
HyperlinkGene Summary
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD2 antigen (cytoplasmic tail) binding protein 2|CD2 binding protein 2|CD2 cytoplasmic domain binding protein 2|U5 snRNP 52K protein
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Interactome
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