NDC80 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human NDC80.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (84)
Quality Control Testing
Standard curve using NDC80 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 243x to 3x dilution of the NDC80 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-NDC80 (100 ug)
2. Detection antibody: rabbit purified polyclonal anti-NDC80 (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — NDC80
Entrez GeneID
10403Gene Name
NDC80
Gene Alias
HEC, HEC1, KNTC2, TID3, hsNDC80
Gene Description
NDC80 homolog, kinetochore complex component (S. cerevisiae)
Omim ID
607272Gene Ontology
HyperlinkGene Summary
HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM
Other Designations
highly expressed in cancer, rich in leucine heptad repeats|kinetochore associated 2
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Interactome
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Disease
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