PEMT rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PEMT peptide using ARM Technology.
Immunogen
A synthetic peptide of human PEMT is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PEMT peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PEMT
Entrez GeneID
10400GeneBank Accession#
PEMTGene Name
PEMT
Gene Alias
MGC2483, PEAMT, PEMPT, PEMT2, PNMT
Gene Description
phosphatidylethanolamine N-methyltransferase
Omim ID
602391Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000065536|OTTHUMP00000065537
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