DLC1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DLC1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DLC1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DLC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DLC1
Entrez GeneID
10395GeneBank Accession#
DLC1Gene Name
DLC1
Gene Alias
ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Gene Description
deleted in liver cancer 1
Omim ID
604258Gene Ontology
HyperlinkGene Summary
This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000116050|Rho-GTPase-activating protein 7|START domain containing protein 12|StAR-related lipid transfer (START) domain containing 12|StAR-related lipid transfer protein 12|deleted in liver cancer 1 variant 2
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Interactome
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Disease
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