BPNT1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BPNT1 full-length
Host
Human
Theoretical MW (kDa)
28.82
Interspecies Antigen Sequence
Mouse (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BPNT1 antibody (H00010380-B01) by Western Blots.
Western Blot
Lane 1: BPNT1 transfected lysate ( 28.1 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
BPNT1 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BPNT1
Entrez GeneID
10380GeneBank Accession#
NM_006085Protein Accession#
NP_006076Gene Name
BPNT1
Gene Alias
PIP
Gene Description
3'(2'), 5'-bisphosphate nucleotidase 1
Omim ID
604053Gene Ontology
HyperlinkGene Summary
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq
Other Designations
BPntase|OTTHUMP00000035564|PAP-inositol-1,4-phosphatase|bisphosphate 3'-nucleotidase
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Interactome
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