TRIM22 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
TRIM22 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM22 expression in human colon.
Immunoprecipitation
Immunoprecipitation of TRIM22 transfected lysate using anti-TRIM22 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TRIM22 purified MaxPab mouse polyclonal antibody (B01P) (H00010346-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TRIM22 protein.
Immunogen
TRIM22 (NP_006065.2, 1 a.a. ~ 498 a.a) full-length human protein.
Sequence
MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPWNCLVPMTVCPPSS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TRIM22 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM22 expression in human colon.Immunoprecipitation
Immunoprecipitation of TRIM22 transfected lysate using anti-TRIM22 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TRIM22 purified MaxPab mouse polyclonal antibody (B01P) (H00010346-B01P). -
Gene Info — TRIM22
Entrez GeneID
10346GeneBank Accession#
BC035582.1Protein Accession#
NP_006065.2Gene Name
TRIM22
Gene Alias
GPSTAF50, RNF94, STAF50
Gene Description
tripartite motif-containing 22
Omim ID
606559Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. [provided by RefSeq
Other Designations
OTTHUMP00000069823|stimulated trans-acting factor (50 kDa)|tripartite binding motif 22|tripartite motif protein TRIM22
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Interactome
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Publication Reference
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Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines.
Turrini F, Saliu F, Forlani G, Das AT, Van Lint C, Accolla RS, Berkhout B, Poli G, Vicenzi E.
Virus Research 2019 Aug; 269:197631.
Application：IP, WB-Tr, Human, HEK 293T cells.
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Variants in TRIM22 that Affect NOD2 Signaling Are Associated With Very Early Onset Inflammatory Bowel Disease .
Li Q, Lee CH, Peters LA, Mastropaolo LA, Thoeni C, Elkadri A, Schwerd T, Zhu J, Zhang B, Zhao Y, Hao K, Dinarzo A, Hoffman G, Kidd B, Murchie R, Adham ZA, Guo C, Kotlarz D, Cutz E, Walters TD, Shouval DS, Curran M, Dobrin R, Brodmerkel C, Snapper SB, Klein C.
Gastroenterology 2016 May; 150(5):1196.
Application：IP, Human, HEK 293 cells.
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Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines.
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