SIRPB1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SIRPB1 full-length
Host
Human
Theoretical MW (kDa)
19.4
Interspecies Antigen Sequence
Mouse (51)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SIRPB1 antibody (H00010326-B01) by Western Blots.
SDS-PAGE Gel
SIRPB1 transfected lysate
Western Blot
Lane 1: SIRPB1 transfected lysate ( 19.4 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SIRPB1
Entrez GeneID
10326GeneBank Accession#
BC075835Protein Accession#
-Gene Name
SIRPB1
Gene Alias
CD172b, DKFZp686A05192, FLJ26614, SIRP-BETA-1
Gene Description
signal-regulatory protein beta 1
Omim ID
603889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029992|OTTHUMP00000029993
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