SIRPB1 MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SIRPB1 protein.
Immunogen
SIRPB1 (AAH75835.1, 1 a.a. ~ 181 a.a) full-length human protein.
Sequence
MPVPASWPHLPSPFLLMTLLLGRLTGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVREPALAPTAPLLVALLLGPKLLLVVGVSAIYICWKQKA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (51)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SIRPB1 expression in transfected 293T cell line (H00010326-T01) by SIRPB1 MaxPab polyclonal antibody.
Lane 1: SIRPB1 transfected lysate(19.91 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SIRPB1
Entrez GeneID
10326GeneBank Accession#
BC075835Protein Accession#
AAH75835.1Gene Name
SIRPB1
Gene Alias
CD172b, DKFZp686A05192, FLJ26614, SIRP-BETA-1
Gene Description
signal-regulatory protein beta 1
Omim ID
603889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029992|OTTHUMP00000029993
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