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Last updated: 2016/11/27

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TCIRG1 rabbit monoclonal antibody

  • Catalog # : H00010312-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TCIRG1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TCIRG1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TCIRG1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • TCIRG1
  • Gene Alias:
  • ATP6N1C,ATP6V0A3,Atp6i,OC-116kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3
  • Gene Description:
  • T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
  • Gene Summary:
  • Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq
  • Other Designations:
  • ATPase, H+ transporting, 116kD,T cell immune response cDNA7 protein,T-cell immune regulator 1,T-cell, immune regulator 1,T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3,T-cell, immune regulator 1, ATPase, H+ transporting, lyso
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