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PAK4 Pre-design Chimera RNAi

  • Catalog # : H00010298-R08
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens p21(CDKN1A)-activated kinase 4 (PAK4), transcript variant 5, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001014834
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • PAK4
  • Gene Alias:
  • -
  • Gene Description:
  • p21 protein (Cdc42/Rac)-activated kinase 4
  • Gene Summary:
  • PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • p21(CDKN1A)-activated kinase 4,p21-activated kinase 4,protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
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