MAEA (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human MAEA full-length ORF ( AAH06470, 1 a.a. - 385 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTLKVQEYPTLKVPYETLNKRFRAAQKNIDREASHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEELSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
68.09
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAEA
Entrez GeneID
10296GeneBank Accession#
BC006470Protein Accession#
AAH06470Gene Name
MAEA
Gene Alias
EMLP, EMP, HLC-10, PIG5
Gene Description
macrophage erythroblast attacher
Omim ID
606801Gene Ontology
HyperlinkGene Summary
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
Other Designations
erythroblast macrophage protein|lung cancer-related protein 10|proliferation-inducing gene 5
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