DSCR4 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human DSCR4 full-length ORF ( ADR82732.1, 1 a.a. - 118 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSLIILTRDDEPRIFTPDSDAASPALHSTSPLPDPASASPLHREEKILPKVCNIVSCLSFSLPASPTDSGLASPTIITREGQQFWAKCLIWKYQLYLHGLHKKSDGRRDKQISASPST
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
13
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DSCR4
Entrez GeneID
10281GeneBank Accession#
HQ257978.1Protein Accession#
ADR82732.1Gene Name
DSCR4
Gene Alias
DCRB, DSCRB
Gene Description
Down syndrome critical region gene 4
Omim ID
604829Gene Ontology
HyperlinkGene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq
Other Designations
Down syndrome critical region protein 4|Down syndrome critical region protein B
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