SIGMAR1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SIGMAR1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SIGMAR1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SIGMAR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SIGMAR1
Entrez GeneID
10280GeneBank Accession#
SIGMAR1Gene Name
SIGMAR1
Gene Alias
FLJ25585, MGC3851, OPRS1, SR-BP1
Gene Description
sigma non-opioid intracellular receptor 1
Omim ID
601978Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000000515|OTTHUMP00000000516|OTTHUMP00000000517|OTTHUMP00000021286|SR31747 binding protein 1|aging-associated gene 8 protein|opioid receptor, sigma 1|sigma1 receptor|type I sigma receptor
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Interactome
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