ZMPSTE24 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ZMPSTE24 full-length ORF ( AAH37283.1, 1 a.a. - 475 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGTLILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALAGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVLNKDIQEDSGMEPRNEEEGNSEEIKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRKELFAAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSMWHYSHPPLLERLQALKTMKQH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
81.2
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ZMPSTE24
Entrez GeneID
10269GeneBank Accession#
BC037283.1Protein Accession#
AAH37283.1Gene Name
ZMPSTE24
Gene Alias
FACE-1, FACE1, FLJ14968, STE24, Ste24p
Gene Description
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq
Other Designations
CAAX prenyl protease|OTTHUMP00000006394|farnesylated-proteins converting enzyme 1|prenyl protein-specific endoprotease 1|zinc metalloproteinase STE24
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Interactome
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Disease
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