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Last updated: 2017/12/10

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ZMPSTE24 rabbit monoclonal antibody

  • Catalog # : H00010269-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ZMPSTE24 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ZMPSTE24 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ZMPSTE24 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • ZMPSTE24
  • Gene Alias:
  • FACE-1,FACE1,FLJ14968,STE24,Ste24p
  • Gene Description:
  • zinc metallopeptidase (STE24 homolog, S. cerevisiae)
  • Gene Summary:
  • This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq
  • Other Designations:
  • CAAX prenyl protease,OTTHUMP00000006394,farnesylated-proteins converting enzyme 1,prenyl protein-specific endoprotease 1,zinc metalloproteinase STE24
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