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Last updated: 2016/12/4

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SF3B4 rabbit monoclonal antibody

  • Catalog # : H00010262-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SF3B4 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SF3B4 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SF3B4 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • SF3B4
  • Gene Name:
  • SF3B4
  • Gene Alias:
  • MGC10828,SAP49,SF3b49
  • Gene Description:
  • splicing factor 3b, subunit 4, 49kDa
  • Gene Summary:
  • This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000014064,pre-mRNA splicing factor SF3b 49 kDa subunit,spliceosomal protein,spliceosome-associated protein (U2 snRNP),splicing factor 3b, subunit 4
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