STAM2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human STAM2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human STAM2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human STAM2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — STAM2
Entrez GeneID
10254GeneBank Accession#
STAM2Gene Name
STAM2
Gene Alias
DKFZp564C047, Hbp, STAM2A, STAM2B
Gene Description
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Omim ID
606244Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq
Other Designations
Hrs-binding protein|STAM-like protein containing SH3 and ITAM domains 2|signal transducing adaptor molecule 2
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Interactome
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Pathway
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