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Last updated: 2016/10/23

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SPRY2 Pre-design Chimera RNAi

  • Catalog # : H00010253-R01
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  • Specification
  • Product Description:
  • Homo sapiens sprouty homolog 2 (Drosophila) (SPRY2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005842
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • SPRY2
  • Gene Alias:
  • MGC23039,hSPRY2
  • Gene Description:
  • sprouty homolog 2 (Drosophila)
  • Gene Summary:
  • This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018543,OTTHUMP00000018544,sprouty 2
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