RASGRP2 monoclonal antibody (M01), clone 1E5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RASGRP2.
Immunogen
RASGRP2 (NP_005816, 65 a.a. ~ 164 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — RASGRP2
Entrez GeneID
10235GeneBank Accession#
NM_005825Protein Accession#
NP_005816Gene Name
RASGRP2
Gene Alias
CALDAG-GEFI, CDC25L
Gene Description
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Omim ID
605577Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000042931|OTTHUMP00000069245|OTTHUMP00000069246|RAS guanyl nucleotide-releasing protein 2|RAS guanyl releasing protein 2|calcium and DAG-regulated guanine nucleotide exchange factor I|calcium and diacylglycerol-regulated guanine nucleotide exchan
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Interactome
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Pathway
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