Rabbit monoclonal antibody raised against a human RASGRP2 peptide using ARM Technology.
A synthetic peptide of human RASGRP2 is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Quality Control Testing:
Antibody reactive against human RASGRP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
In 1x PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
OTTHUMP00000042931,OTTHUMP00000069245,OTTHUMP00000069246,RAS guanyl nucleotide-releasing protein 2,RAS guanyl releasing protein 2,calcium and DAG-regulated guanine nucleotide exchange factor I,calcium and diacylglycerol-regulated guanine nucleotide exchan