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PLIN3 rabbit monoclonal antibody

  • Catalog # : H00010226-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PLIN3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PLIN3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PLIN3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • PLIN3
  • Gene Name:
  • PLIN3
  • Gene Alias:
  • MGC11117,MGC2012,PP17,TIP47,M6PRBP1
  • Gene Description:
  • mannose-6-phosphate receptor binding protein 1
  • Gene Summary:
  • Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • MPR-BINDING PROTEIN, 47-KD,MPR-binding protein 47 kDa,cargo selection protein (mannose 6 phosphate receptor binding protein),cargo selection protein TIP47,mannose 6 phosphate receptor binding protein 1,placental protein 17,tail-interacting protein, 47 kD
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