KLRG1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human KLRG1 full-length ORF ( NP_005801.3, 1 a.a. - 189 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTDSVIYSMLELPTATQAQNDYGPQQKSSSSRPSCSCLVAIALGLLTAVLLSVLLYQWILCQGSNYSTCASCPSCPDRWMKYGNHCYYFSVEEKDWNSSLEFCLARDSHLLVITDNQEMSLLQVFLSEAFCWIGLRNNSGWRWEDGSPLNFSRISSNSFVQTCGAINKNGLQASSCEVPLHWVCKKVRL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
47.6
Interspecies Antigen Sequence
Mouse (56); Rat (54)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KLRG1
Entrez GeneID
10219GeneBank Accession#
NM_005810.3Protein Accession#
NP_005801.3Gene Name
KLRG1
Gene Alias
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, MGC13600
Gene Description
killer cell lectin-like receptor subfamily G, member 1
Omim ID
604874Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq
Other Designations
C-type lectin domain family 15, member A|mast cell function-associated antigen (ITIM-containing)
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Interactome
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Disease
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