KLRG1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KLRG1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KLRG1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KLRG1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KLRG1
Entrez GeneID
10219GeneBank Accession#
KLRG1Gene Name
KLRG1
Gene Alias
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, MGC13600
Gene Description
killer cell lectin-like receptor subfamily G, member 1
Omim ID
604874Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq
Other Designations
C-type lectin domain family 15, member A|mast cell function-associated antigen (ITIM-containing)
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Interactome
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Disease
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