KLRG1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant KLRG1.
Immunogen
KLRG1 (NP_005801, 57 a.a. ~ 119 a.a) partial recombinant protein with GST tag.
Sequence
QWILCQGSNYSTCASCPSCPDRWMKYGNHCYYFSVEEKDWNSSLEFCLARDSHLLVITDNQEM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (56); Rat (54)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.04 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — KLRG1
Entrez GeneID
10219GeneBank Accession#
NM_005810Protein Accession#
NP_005801Gene Name
KLRG1
Gene Alias
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, MGC13600
Gene Description
killer cell lectin-like receptor subfamily G, member 1
Omim ID
604874Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq
Other Designations
C-type lectin domain family 15, member A|mast cell function-associated antigen (ITIM-containing)
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Interactome
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Disease
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Publication Reference
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Cell-to-Cell Contact with Hepatitis C Virus-Infected Cells Reduces Functional Capacity of Natural Killer Cells.
Yoon JC, Lim JB, Park JH, Lee JM.
Journal of Virology 2011 Dec; 85(23):12557.
Application:Flow Cyt, Human, Huh7, Huh7.5 cells.
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Cell-to-Cell Contact with Hepatitis C Virus-Infected Cells Reduces Functional Capacity of Natural Killer Cells.
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