MPZL2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MPZL2 transfected lysate using rabbit polyclonal anti-MPZL2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MPZL2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-MPZL2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-MPZL2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — MPZL2
Entrez GeneID
10205Gene Name
MPZL2
Gene Alias
EVA, EVA1
Gene Description
myelin protein zero-like 2
Omim ID
604873Gene Ontology
HyperlinkGene Summary
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
epithelial V-like antigen 1
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