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Last updated: 2016/10/16
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PSME3 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00010197-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human PSME3 protein.
  • Immunogen:
  • PSME3 (AAH01423, 1 a.a. ~ 254 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of PSME3 expression in transfected 293T cell line (H00010197-T01) by PSME3 MaxPab polyclonal antibody.

    Lane 1: PSME3 transfected lysate(28.05 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • PSME3
  • Gene Alias:
  • Ki,PA28-gamma,PA28G,REG-GAMMA
  • Gene Description:
  • proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • 11S regulator complex gamma subunit,Ki antigen,Ki nuclear autoantigen,activator of multicatalytic protease subunit 3,proteasome activator 28-gamma,proteasome activator subunit 3
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