TNK2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Cell lysate)
TNK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of TNK2 expression in IMR-32.
Western Blot (Transfected lysate)
Western Blot analysis of TNK2 expression in transfected 293T cell line (H00010188-T02) by TNK2 MaxPab polyclonal antibody.
Lane 1: TNK2 transfected lysate(39.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of TNK2 transfected lysate using anti-TNK2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TNK2 purified MaxPab mouse polyclonal antibody (B01P) (H00010188-B01P).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TNK2 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TNK2 protein.
Immunogen
TNK2 (AAH08884.1, 1 a.a. ~ 352 a.a) full-length human protein.
Sequence
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFVVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKPPWRDISASSSTQFPHAVPCFPTSLLAKLLLRHSVPASSREIKLVSILC
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TNK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of TNK2 expression in IMR-32.Western Blot (Transfected lysate)
Western Blot analysis of TNK2 expression in transfected 293T cell line (H00010188-T02) by TNK2 MaxPab polyclonal antibody.
Lane 1: TNK2 transfected lysate(39.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of TNK2 transfected lysate using anti-TNK2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TNK2 purified MaxPab mouse polyclonal antibody (B01P) (H00010188-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TNK2 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — TNK2
Entrez GeneID
10188GeneBank Accession#
BC008884.2Protein Accession#
AAH08884.1Gene Name
TNK2
Gene Alias
ACK, ACK1, FLJ44758, FLJ45547, p21cdc42Hs
Gene Description
tyrosine kinase, non-receptor, 2
Omim ID
606994Gene Ontology
HyperlinkGene Summary
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq
Other Designations
activated Cdc42-associated kinase 1|activated p21cdc42Hs kinase
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