Products

Western Blot (Transfected lysate)

Western Blot analysis of SLC25A13 expression in transfected 293T cell line by SLC25A13 monoclonal antibody (M01), clone 4F4.

Lane 1: SLC25A13 transfected lysate(74.2 KDa).
Lane 2: Non-transfected lysate.

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged SLC25A13 is approximately 0.3ng/ml as a capture antibody.

ELISA

RNAi Knockdown (Antibody validated)

Western blot analysis of SLC25A13 over-expressed 293 cell line, cotransfected with SLC25A13 Validated Chimera RNAi ( Cat # H00010165-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with SLC25A13 monoclonal antibody (M01), clone 4F4 (Cat # H00010165-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Immunofluorescence

Immunofluorescence of monoclonal antibody to SLC25A13 on HepG2 cell. [antibody concentration 10 ug/ml]

Entrez GeneID

10165

GeneBank Accession#

NM_014251

Protein Accession#

NP_055066

Gene Name

SLC25A13

Gene Alias

ARALAR2, CITRIN, CTLN2

Gene Description

solute carrier family 25, member 13 (citrin)

Omim ID

603471 603859 605814

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

mitochondrial aspartate glutamate carrier 2