EBI3 monoclonal antibody (M01), clone 1D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant EBI3. (Please notice that this antibody can't conjugate with biotin, biotinylation will lead to lost of antibody specificity).
Immunogen
EBI3 (NP_005746, 129 a.a. ~ 229 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (62); Rat (62)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EBI3 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — EBI3
Entrez GeneID
10148GeneBank Accession#
NM_005755Protein Accession#
NP_005746Gene Name
EBI3
Gene Alias
IL27B
Gene Description
Epstein-Barr virus induced 3
Omim ID
605816Gene Ontology
HyperlinkGene Summary
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq
Other Designations
Epstein-Barr virus induced gene 3|cytokine receptor|interleukin-27 subunit beta
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