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TOB1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00010140-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TOB1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 38.06
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TOB1 antibody (H00010140-B01) by Western Blots.
    Western Blot
    QC Testing of H00010140-T01
    Lane 1: TOB1 transfected lysate ( 38.2 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00010140-T01
    TOB1 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • TOB1
  • Gene Alias:
  • APRO6,MGC104792,MGC34446,PIG49,TOB,TROB,TROB1
  • Gene Description:
  • transducer of ERBB2, 1
  • Gene Summary:
  • This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells. [provided by RefSeq
  • Other Designations:
  • transducer of erbB-2
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