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OPTN 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00010133-T02
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-OPTN full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 65.9
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-OPTN antibody (H00010133-B01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00010133-T02
    OPTN transfected lysate.
    Western Blot
    QC Testing of H00010133-T02
    Lane 1: OPTN transfected lysate ( 65.90 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • OPTN
  • Gene Alias:
  • Gene Description:
  • optineurin
  • Gene Summary:
  • This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • Huntingtin interacting protein L,OTTHUMP00000019125,OTTHUMP00000019126,OTTHUMP00000019127,OTTHUMP00000019128,glaucoma 1, open angle, E (adult-onset),nemo-related protein,transcrption factor IIIA-interacting protein,tumor necrosis factor alpha-inducible ce
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