OPTN (Human) IP-WB Antibody Pair
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunoprecipitation of OPTN transfected lysate using rabbit polyclonal anti-OPTN and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-OPTN.
-
Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (73)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of OPTN transfected lysate using rabbit polyclonal anti-OPTN and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-OPTN.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-OPTN (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-OPTN (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
-
Applications
Immunoprecipitation-Western Blot
-
Gene Info — OPTN
Entrez GeneID
10133Gene Name
OPTN
Gene Alias
FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Gene Description
optineurin
Gene Ontology
HyperlinkGene Summary
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
Huntingtin interacting protein L|OTTHUMP00000019125|OTTHUMP00000019126|OTTHUMP00000019127|OTTHUMP00000019128|glaucoma 1, open angle, E (adult-onset)|nemo-related protein|transcrption factor IIIA-interacting protein|tumor necrosis factor alpha-inducible ce
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com