PDIA6 monoclonal antibody (M04), clone 3B4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PDIA6.
Immunogen
PDIA6 (AAH01312, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDRNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEGDIDLSDVELDDLGKDEL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (74.14 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PDIA6 expression in transfected 293T cell line by PDIA6 monoclonal antibody (M04), clone 3B4.
Lane 1: PDIA6 transfected lysate(48.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDIA6 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — PDIA6
Entrez GeneID
10130GeneBank Accession#
BC001312Protein Accession#
AAH01312Gene Name
PDIA6
Gene Alias
ERP5, P5, TXNDC7
Gene Description
protein disulfide isomerase family A, member 6
Omim ID
611099Gene Ontology
HyperlinkGene Summary
Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM
Other Designations
endoplasmic reticulum protein 5|protein disulfide isomerase-associated 6|protein disulfide isomerase-related protein|thioredoxin domain containing 7 (protein disulfide isomerase)
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Interactome
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Disease
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Publication Reference
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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients.
Sasha E Stanton, Ekram Gad, Erik Ramos, Lauren Corulli, James Annis, Jennifer Childs, Hiroyuki Katayama, Samir Hanash, Jeffrey Marks, Mary L Disis.
NPJ Breast Cancer 2021 May; 7(1):50.
Application:Cap Ab, ELISA, Human, Human serum.
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Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress.
Lee S, Min Kim S, Dotimas J, Li L, Feener EP, Baldus S, Myers RB, Chutkow WA, Patwari P, Yoshioka J, Lee RT.
EMBO Molecular Medicine 2014 Jun; 6(6):732.
Application:Pull-Down, WB-Tr, Human, HEK293TN cells.
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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients.
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