ACTR1B monoclonal antibody (M05), clone 4E10
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More Files
- More Functions
Immunofluorescence
Immunofluorescence of monoclonal antibody to ACTR1B on HeLa cell . [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ACTR1B.
Immunogen
ACTR1B (NP_005726, 191 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHK*
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ACTR1B on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ACTR1B
Entrez GeneID
10120GeneBank Accession#
NM_005735Protein Accession#
NP_005726Gene Name
ACTR1B
Gene Alias
ARP1B, CTRN2, PC3
Gene Description
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
Omim ID
605144Gene Ontology
HyperlinkGene Summary
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq
Other Designations
ARP1 actin-related protein 1 homolog B, centractin beta|centractin beta
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