ENAM monoclonal antibody (M01), clone 2C12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ENAM.
Immunogen
ENAM (NP_114095, 1043 a.a. ~ 1141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ERQQQRPSNILHLPCFGSKLAKHHSSTTGTPSSDGRQSPFDGDSITPTENPNTLVELATEEQFKSINVDPLDADEHSPFEFLQRGTNVQDQVQDCLLLQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (43); Rat (42)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ENAM is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ENAM
Entrez GeneID
10117GeneBank Accession#
NM_031889Protein Accession#
NP_114095Gene Name
ENAM
Gene Alias
ADAI, AI1C, AIH2
Gene Description
enamelin
Gene Ontology
HyperlinkGene Summary
Dental enamel is a highly mineralized tissue with 85% of its volume occupied by unusually large, highly organized, hydroxyapatite crystals. This highly organized and unusual structure is thought to be rigorously controlled in ameloblasts through the interaction of a number of organic matrix molecules that include enamelin, amelogenin (AMELX; MIM 300391), ameloblastin (AMBN; MIM 601259), tuftelin (TUFT1; MIM 600087), dentine sialophosphoprotein (DSPP; MIM 125485), and a variety of enzymes. Enamelin is the largest protein in the enamel matrix of developing teeth and comprises approximately 5% of total enamel matrix protein.[supplied by OMIM
Other Designations
OTTHUMP00000160363|amelogenesis imperfecta 2, hypocalcification (autosomal dominant)
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Interactome
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Disease
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