COX17 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human COX17 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — COX17
Entrez GeneID
10063GeneBank Accession#
NM_005694.1Protein Accession#
NP_005685.1Gene Name
COX17
Gene Alias
MGC104397, MGC117386
Gene Description
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
Omim ID
604813Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq
Other Designations
COX17 homolog, cytochrome c oxidase assembly protein|human homolog of yeast mitochondrial copper recruitment
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