DNAJB6 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DNAJB6 protein.
Immunogen
DNAJB6 (NP_490647.1, 1 a.a. ~ 326 a.a) full-length human protein.
Sequence
MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGVADDDALAEERMRRGQNALPAQPAGLRPPKPPRPASLLRHAPHCLSEEEGEQDRPRAPGPWDPLASAAGLKEGGKRKKQKQREESKKKKSTKGNH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (78)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DNAJB6 expression in transfected 293T cell line (H00010049-T01) by DNAJB6 MaxPab polyclonal antibody.
Lane 1: DNAJB6 transfected lysate(35.86 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DNAJB6 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DNAJB6
Entrez GeneID
10049GeneBank Accession#
NM_058246.3Protein Accession#
NP_490647.1Gene Name
DNAJB6
Gene Alias
DJ4, DKFZp566D0824, DnaJ, FLJ42837, HHDJ1, HSJ-2, HSJ2, MGC1152, MGC117297, MRJ, MSJ-1
Gene Description
DnaJ (Hsp40) homolog, subfamily B, member 6
Omim ID
611332Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq
Other Designations
DnaJ-like 2 protein|heat shock protein J2
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Interactome
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Publication Reference
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Micro-RNA-632 downregulates DNAJB6 in breast cancer.
Mitra A, Rostas JW, Dyess DL, Shevde LA, Samant RS.
Laboratory Investigation 2012 Sep; 92(9):1310.
Application:WB-Tr, Human, MCF-10A, MDA-MB-231 cells.
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Micro-RNA-632 downregulates DNAJB6 in breast cancer.
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