PARP2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PARP2 partial ORF ( NP_005475.1, 435 a.a. - 534 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (82); Rat (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PARP2
Entrez GeneID
10038GeneBank Accession#
NM_005484Protein Accession#
NP_005475.1Gene Name
PARP2
Gene Alias
ADPRT2, ADPRTL2, ADPRTL3, PARP-2, pADPRT-2
Gene Description
poly (ADP-ribose) polymerase 2
Omim ID
607725Gene Ontology
HyperlinkGene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq
Other Designations
ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2|poly (ADP-ribose) polymerase family, member 2|poly (ADP-ribosyl) transferase-like 2|poly(ADP-ribose) synthetase
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Interactome
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Pathway
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Disease
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