FRAT1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human FRAT1 partial ORF (NP_005470.2, 181 a.a. - 279 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (89); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FRAT1
Entrez GeneID
10023GeneBank Accession#
NM_005479.3Protein Accession#
NP_005470.2Gene Name
FRAT1
Gene Alias
FLJ97193
Gene Description
frequently rearranged in advanced T-cell lymphomas
Omim ID
602503Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq
Other Designations
GSK-3 binding protein FRAT1|OTTHUMP00000020201|OTTHUMP00000059391|proto-oncogene FRAT1
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Interactome
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Pathway
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Disease
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