PDCD6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PDCD6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PDCD6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PDCD6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PDCD6
Entrez GeneID
10016GeneBank Accession#
PDCD6Gene Name
PDCD6
Gene Alias
ALG-2, FLJ46208, MGC111017, MGC119050, MGC9123, PEF1B
Gene Description
programmed cell death 6
Omim ID
601057Gene Ontology
HyperlinkGene Summary
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. [provided by RefSeq
Other Designations
apoptosis-linked gene 2|apoptosis-linked gene-2
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Interactome
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Toll Free : +1-877-853-6098 - +1-909-992-3401
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