PDCD6IP 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
PDCD6IP transfected lysate.
Western Blot
Lane 1: PDCD6IP transfected lysate ( 96.00 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PDCD6IP full-length
Host
Human
Theoretical MW (kDa)
96
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PDCD6IP antibody (H00010015-D01P) by Western Blots.
SDS-PAGE Gel
PDCD6IP transfected lysate.
Western Blot
Lane 1: PDCD6IP transfected lysate ( 96.00 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PDCD6IP
Entrez GeneID
10015GeneBank Accession#
NM_013374Protein Accession#
AAH20066.1Gene Name
PDCD6IP
Gene Alias
AIP1, Alix, DRIP4, HP95, MGC17003
Gene Description
programmed cell death 6 interacting protein
Omim ID
608074Gene Ontology
HyperlinkGene Summary
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ALG-2 interacting protein 1|ALG-2 interacting protein X|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death 6-interacting protein
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Interactome
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Pathway
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Disease
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