This antibody pair set comes with matched antibody pair to detect and quantify protein level of human PDCD6IP.
Quality Control Testing:
Standard curve using PDCD6IP 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 81x to 3x dilution of the PDCD6IP 293T overexpression lysate (non-denatured).
Antibody pair set content: 1. Capture antibody: mouse monoclonal anti-PDCD6IP (100 ug) 2. Detection antibody: rabbit purified polyclonal anti-PDCD6IP (50 ug) *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
ALG-2 interacting protein 1,ALG-2 interacting protein X,apoptosis-linked gene 2-interacting protein X,dopamine receptor interacting protein 4,programmed cell death 6-interacting protein