TANK 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
TANK transfected lysate
Western Blot
Lane 1: TANK transfected lysate ( 13.2 KDa).
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TANK full-length
Host
Human
Theoretical MW (kDa)
13.2
Interspecies Antigen Sequence
Mouse (79); Rat (78)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TANK antibody (H00010010-B01) by Western Blots.
SDS-PAGE Gel
TANK transfected lysate
Western Blot
Lane 1: TANK transfected lysate ( 13.2 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TANK
Entrez GeneID
10010GeneBank Accession#
BC003388Protein Accession#
AAH03388Gene Name
TANK
Gene Alias
I-TRAF, TRAF2
Gene Description
TRAF family member-associated NFKB activator
Omim ID
603893Gene Ontology
HyperlinkGene Summary
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
TRAF family member-associated NF-KAPPA-B activator|TRAF interacting protein TANK
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Interactome
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Disease
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