ACOT8 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ACOT8 protein.
Immunogen
ACOT8 (NP_005460.2, 1 a.a. ~ 319 a.a) full-length human protein.
Sequence
MSSPQAPEDGQGCGDRGDPPGDLRSVLVTTVLNLEPLDEDLFRGRHYWVPAKRLFGGQIVGQALVAAAKSVSEDVHVHSLHCYFVRAGDPKLPVLYQVERTRTGSSFSVRSVKAVQHGKPIFICQASFQQAQPSPMQHQFSMPTVPPPEELLDCETLIDQYLRDPNLQKRYPLALNRIAAQEVPIEIKPVNPSPLSQLQRMEPKQMFWVRARGYIGEGDMKMHCCVAAYISDYAFLGTALLPHQWQHKVHFMVSLDHSMWFHAPFRADHWMLYECESPWAGGSRGLVHGRLWRQDGVLAVTCAQEGVIRVKPQVSESKL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACOT8 expression in transfected 293T cell line (H00010005-T01) by ACOT8 MaxPab polyclonal antibody.
Lane 1: ACOT8 transfected lysate(35.09 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ACOT8 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ACOT8
Entrez GeneID
10005GeneBank Accession#
NM_005469.2Protein Accession#
NP_005460.2Gene Name
ACOT8
Gene Alias
HNAACTE, PTE-2, PTE1, PTE2, hACTE-III, hTE
Gene Description
acyl-CoA thioesterase 8
Omim ID
608123Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
HIV-Nef associated acyl-CoA thioesterase|OTTHUMP00000031675|long-chain fatty-acyl-CoA hydrolase|palmitoyl-CoA hydrolase|peroxisomal acyl-CoA thioesterase 1|peroxisomal acyl-coenzyme A thioester hydrolase 1|peroxisomal long-chain acyl-CoA thioesterase 1|th
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Interactome
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