NR2E3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NR2E3 full-length
Host
Human
Theoretical MW (kDa)
44.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NR2E3 antibody (H00010002-D01P) by Western Blots.
SDS-PAGE Gel
NR2E3 transfected lysate.
Western Blot
Lane 1: NR2E3 transfected lysate ( 44.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NR2E3
Entrez GeneID
10002GeneBank Accession#
NM_014249.2Protein Accession#
NP_055064.1Gene Name
NR2E3
Gene Alias
ESCS, MGC49976, PNR, RNR, RP37, rd7
Gene Description
nuclear receptor subfamily 2, group E, member 3
Gene Ontology
HyperlinkGene Summary
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
photoreceptor-specific nuclear receptor|retina-specific nuclear receptor
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Interactome
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Disease
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